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home:pathogenesis:familial_aggregation [06.09.2010] – paulalberthome:pathogenesis:familial_aggregation [06.09.2010] – paulalbert
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 The reigning explanation for familial aggregation is that people pass down faulty genes to their offspring.  However, the theory is not supported by solid evidence.  Scientists have failed to find genes that might cause any major chronic inflammatory disease.  In the case that they have found a relationship between a gene and a disease, statistical significance is usually so low that environmental influences such as bacteria could easily be causing the genetic mutations.  To date, no form of gene therapy has proven effective for treating inflammatory disease. The reigning explanation for familial aggregation is that people pass down faulty genes to their offspring.  However, the theory is not supported by solid evidence.  Scientists have failed to find genes that might cause any major chronic inflammatory disease.  In the case that they have found a relationship between a gene and a disease, statistical significance is usually so low that environmental influences such as bacteria could easily be causing the genetic mutations.  To date, no form of gene therapy has proven effective for treating inflammatory disease.
      
-===== Th1 pathogens are passed among family members =====+===== Families =====
  
 <relatedarticle> [[home:pathogenesis:transmission|Transmission of bacteria and onset of chronic disease]] </article> <relatedarticle> [[home:pathogenesis:transmission|Transmission of bacteria and onset of chronic disease]] </article>
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 The Th1 pathogens gradually mutate genetic pathways and cause disease by a process known as successive infection. The Th1 pathogens gradually mutate genetic pathways and cause disease by a process known as successive infection.
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 ==== Spouses develop the same diseases ==== ==== Spouses develop the same diseases ====
    
home/pathogenesis/familial_aggregation.txt · Last modified: 09.14.2022 by 127.0.0.1
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