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home:pathogenesis:familial_aggregation [06.09.2010] – paulalbert | home:pathogenesis:familial_aggregation [07.12.2010] – paulalbert | ||
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The reigning explanation for familial aggregation is that people pass down faulty genes to their offspring. | The reigning explanation for familial aggregation is that people pass down faulty genes to their offspring. | ||
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- | ===== Th1 pathogens are passed among family members | + | ===== Families |
< | < | ||
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The Th1 pathogens gradually mutate genetic pathways and cause disease by a process known as successive infection. | The Th1 pathogens gradually mutate genetic pathways and cause disease by a process known as successive infection. | ||
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==== Spouses develop the same diseases ==== | ==== Spouses develop the same diseases ==== | ||
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When one considers how often chronic diseases co-occur within a family unit – heart disease, arthritis, bipolar disorder, breast cancer, inflammatory bowel disease, Alzheimer’s disease – it becomes increasingly plausible that nearly all inflammatory diseases are communicable and that this communicability results in familial aggregation. | When one considers how often chronic diseases co-occur within a family unit – heart disease, arthritis, bipolar disorder, breast cancer, inflammatory bowel disease, Alzheimer’s disease – it becomes increasingly plausible that nearly all inflammatory diseases are communicable and that this communicability results in familial aggregation. | ||
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===== Non-relations in close proximity develop the same diseases ===== | ===== Non-relations in close proximity develop the same diseases ===== | ||
As would be expected for the Th1 diseases, which are [[home: | As would be expected for the Th1 diseases, which are [[home: | ||
+ | * **Alzheimer' | ||
* **multiple sclerosis** – Multiple sclerosis occurred in epidemic form in various North Atlantic islands: probably in Iceland and the Shetland-Orkneys; | * **multiple sclerosis** – Multiple sclerosis occurred in epidemic form in various North Atlantic islands: probably in Iceland and the Shetland-Orkneys; | ||
* **obesity** – Research suggests that obesity is also an inflammatory disease caused by certain species of the Th1 pathogens. | * **obesity** – Research suggests that obesity is also an inflammatory disease caused by certain species of the Th1 pathogens. |