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home:pathogenesis:microbiota:detecting [08.27.2012] – [Existence of microbes in healthy tissue supposed to be sterile] paulalberthome:pathogenesis:microbiota:detecting [10.13.2018] – [Availability of tests influence which microbes are studied in chronic diseases] sallieq
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 ===== Existence of microbes in healthy tissue supposed to be sterile ===== ===== Existence of microbes in healthy tissue supposed to be sterile =====
  
-  * **blood** – The presence of microbes in the blood is known as bacteremia. While many doctors believe it to be rare, a significant blood microbiome is ubiquitous. The Relman Lab at Stanford used real time PCR to show that there is a substantial and "normal" population of bacterial DNA sequences in the blood of even healthy individuals.(({{pubmed>long:11326021}})) McLaughlin //et al.// used 16S rRNA probes and dark field microscopy to show that the blood of healthy individuals contained pleomorphic microorganisms, which grow slowly and are not susceptible to antibiotics (right).(({{pubmed>long:12454193}})) They concluded that their findings "should not be controversial." +  * **blood** – The presence of microbes in the blood is known as bacteremia. While many doctors believe it to be rare, a significant blood microbiome is ubiquitous. The Relman Lab at Stanford used real time PCR to show that there is a substantial and "normal" population of bacterial DNA sequences in the blood of even healthy individuals.(({{pubmed>long:11326021}})) McLaughlin //et al.// used 16S rRNA probes and dark field microscopy to show that the blood of healthy individuals contained pleomorphic microorganisms, which grow slowly and are not susceptible to antibiotics (right).(({{pubmed>long:12454193}})) They concluded that their findings "should not be controversial." This work has been since confirmed by Moriyama.(({{pubmed>long:18667036}}))
   * **lungs** – Erb-Downward found bacterial 16S sequences in the lung tissues of all subjects in a 2011 based study of healthy patients as well as those with chronic obstructive pulmonary disease (COPD).(({{pubmed>long:21364979}}))   * **lungs** – Erb-Downward found bacterial 16S sequences in the lung tissues of all subjects in a 2011 based study of healthy patients as well as those with chronic obstructive pulmonary disease (COPD).(({{pubmed>long:21364979}}))
  
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-{{tag>Study_Design}}+{{tag>Study_Design Microbes_in_the_human_body}}
  
 ===== Notes and comments ===== ===== Notes and comments =====
home/pathogenesis/microbiota/detecting.txt · Last modified: 09.14.2022 by 127.0.0.1
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